Chengdu Pukang is one of the most professional manufacturers for SNAC with good quality and better price. As regular product usually available in stock.The English name of a raw material drug is API (Active Pharmaceutical Ingredients), which refers to the active ingredients of a drug and are the fundamental substances that constitute its pharmacological effects. Raw materials cannot be directly used by patients and must be further processed into formulations through the addition of excipients and other processes before patients can take them. Intermediates are a type of material produced in the process steps of an API that must undergo further molecular changes or refinement to become an API. The broad industry of raw materials includes APIs and intermediates. SNAC is the absorption enhancer of semaglutide tablets. It is an N-acetylated amino acid derivative synthesized from salicylic acid, which is weakly acidic and amphiphilic. SNAC is the only penetration enhancer approved to improve oral absorption. In other preclinical studies, SNAC has the effect of improving the penetration of peptides (such as insulin) in the intestine. Semaglutide tablets containing SNAC are placed in different volumes of simulated gastric juice, and the pH value gradually changes from acidic to neutral. The smaller the volume, the more obvious the buffering effect; on the contrary, the SNAC-free Semaglutide tablets have no significant effect on the pH value of simulated gastric juice .In view of the significant buffering effect of SNAC, the effect of pH on the stability of semaglutide was investigated in in the presence of pepsin.