Chengdu Pukang is one of the most professional manufacturers for GLP-1 analog intermediates, featured by good quality control, and competitive price. We usually have available goods in stock and can provide from grams to kgs through cold chain logistics for transportation. External modification of side chain is one of the important technologies for long-acting peptides. Pukang has established a peptide long-acting modification platform to provide multiple varieties of modified side chains and side chain fragments, which helps drug development and accelerates the industrialization of pharmaceuticals. We have these Long-acting peptide side chain varieties：Semaglutide side chain (DMF Filing No.039906); Tirzepatide side chain (DMF Filing No. 039989); Insulin Degludec side chain; Icodec insulin side chain; Liraglutide side chain; Long-acting growth hormone side chain; Other customized sidechains and their blocks; Side-chain modifiers are one of the important factors in the pharmacokinetic behavior of peptide products. The development and production of side-chain modifiers of Pukang are carried out in accordance with the requirements of ICH Q11 and other relevant guidelines. According to its structural characteristics and preparation process, potential impact on the quality of peptide drugs, etc., we carry out perfect impurity profiling research and control to ensure the effectiveness and safety of peptide drugs. Semaglutide side chain and Tirzepatide side chain had completed the process verification (50kg) and accumulated dozens of batches, the quality between batches is stable, and the impurity spectrum is consistent.