Understanding chemical compounds is crucial for researchers and scientists working in various fields, including pharmaceuticals and biochemistry. One such compound that has garnered attention is Boc-L-His(Trt)-Aib-OH, known by its unique identifier, 2061897-68-3. This article delves into the properties and potential applications of this short peptide.

What is Boc-L-His(Trt)-Aib-OH?

Boc-L-His(Trt)-Aib-OH is a synthetic peptide that consists of specific amino acid sequences. The term "Boc" refers to the tert-butyloxycarbonyl group, which is commonly used in peptide synthesis to protect the amino end. "L-His(Trt)" stands for L-Histidine with a trityl group, and "Aib" indicates the presence of α-aminoisobutyric acid, a non-standard amino acid known for its role in stabilizing helical structures. The suffix "OH" refers to the free carboxylic acid group, making it a functional component in peptide synthesis.

Properties of 2061897-68-3

This short peptide is recognized for its unique physicochemical properties, which make it valuable in research settings:

· Stability: The presence of Aib contributes to the peptide's structural stability, rendering it resistant to enzymatic degradation. This property is particularly beneficial in drug development, where stability is crucial for therapeutic efficacy.

· Solubility: Boc-L-His(Trt)-Aib-OH is soluble in organic solvents, such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), making it convenient for use in various experimental protocols.

· Purity: High-purity levels are achievable with this compound, ensuring reliable results in experimental applications. The purity is often verified using advanced chromatographic techniques.

Applications in Research

The unique characteristics of 2061897-68-3 open up a range of potential applications:

· Peptide Synthesis: As a building block in the synthesis of larger peptides, Boc-L-His(Trt)-Aib-OH is used to explore protein interactions, study enzyme functions, and develop novel therapeutic agents.

· Biochemical Research: Its stability and solubility make it an ideal candidate for biochemical assays, where it can be used to investigate the mechanisms of action of various enzymes and receptors.

· Pharmaceutical Development: The compound's resistance to degradation makes it a promising candidate for drug development, particularly in designing peptide-d drugs that require extended circulation time in the body.

Conclusion

2061897-68-3, or Boc-L-His(Trt)-Aib-OH, represents a significant component in the toolkit of researchers working on peptide synthesis and biochemical studies. Its stability, solubility, and purity make it a versatile compound with promising applications in drug development and scientific research. As research progresses, the potential uses of this peptide are likely to expand, contributing to advancements in various scientific fields.