Boc-His(Trt)-Aib-Glu(OBtu)-Gly-OH ,CAS number 1890228-73-5 is a sophisticated peptide compound with applications spanning from basic research to drug discovery and development. Its precise composition allows for the synthesis of peptides with specific structural features and functional properties, making it invaluable in biochemical, pharmaceutical, and biomedical sciences. By incorporating various protected amino acids, researchers can tailor peptides for studying biological interactions, developing therapeutic agents, and advancing our understanding of peptide-d biochemistry.The following are specific applications：

1. Solid-Phase Peptide Synthesis (SPPS)：

1)Methodology：Peptides are assembled stepwise on a solid support (such as resin).

2)Role of Boc-His(Trt)-Aib-Glu(OBtu)-Gly-OH(CAS number 1890228-73-5)：It serves as a key building block in peptide chain elongation during SPPS.

3)Coupling：Each protected amino acid in the sequence is sequentially coupled to the growing peptide chain using standard peptide coupling chemistry.

2. Structural and Functional Properties：

1)Enhanced Stability：Incorporation of Aib residues enhances the peptide's conformational stability, crucial for maintaining specific structural motifs or improving resistance to enzymatic degradation.

2)Targeted Functionality：The presence of specific amino acids like His and Glu(OBtu) allows for peptides to exhibit pH-dependent behavior, l ion binding capabilities, or receptor interactions relevant to biological studies.

3. Biomedical and Pharmaceutical Research：

1)Drug Discovery：Peptides synthesized with Boc-His(Trt)-Aib-Glu(OBtu)-Gly-OH(CAS number 1890228-73-5) are used in developing peptide-d therapeutics, including drug candidates targeting specific diseases or physiological processes.

2)Structural Studies：Researchers utilize these peptides to explore structure-activity relationships (SAR), investigating how modifications impact biological activity and therapeutic potential.

4. Analytical and Practical Considerations：

1)Purification：After synthesis, peptides are typically purified using chromatographic methods (e.g., HPLC) to isolate the desired product and remove any impurities.

2)Characterization：Analytical techniques such as mass spectrometry and NMR spectroscopy are employed to confirm the sequence, purity, and structural integrity of synthesized peptides.