Fmoc-Ile-Aib-OH, CAS number 2171139-20-9 plays a critical role in peptide chemistry, enabling the synthesis of peptides with specific structural and functional properties. Its applications are diverse, ranging from fundamental research in biochemistry to potential applications in drug discovery and development. By incorporating amino acids like Isoleucine and Aib, researchers can create peptides with enhanced stability, bioactivity, and potential therapeutic relevance, contributing significantly to advancements in biotechnology and medicine.The following are specific applications：

1. Solid-Phase Peptide Synthesis (SPPS)：

1）Methodology：Peptides are synthesized stepwise on a solid support (such as resin).

2）Role of Fmoc-Ile-Aib-OH(CAS number 2171139-20-9)：It serves as a crucial building block for elongating the peptide chain.

3）Coupling：Fmoc-Ile-Aib-OH(CAS number 2171139-20-9) is coupled to the growing peptide chain using standard peptide coupling chemistry (e.g., carbodiimide coupling).

2. Structural and Functional Modifications：

1）Enhanced Conformational Stability：Incorporation of Aib residues enhances the rigidity of the peptide backbone, influencing its secondary structure and potentially improving stability.

2）Biological Activities：Peptides containing Ile and Aib residues may exhibit specific biological activities such as receptor binding, enzymatic inhibition, or other biofunctional properties.

3. Biomedical and Pharmaceutical Research：

1）Drug Development：Researchers use Fmoc-Ile-Aib-OH(CAS number 2171139-20-9) to synthesize peptide analogs for studying their potential as therapeutic agents, including drug delivery systems or treatments targeting specific biological pathways.

2）Structure-Activity Relationship (SAR) Studies：Peptides synthesized with Fmoc-Ile-Aib-OH(CAS number 2171139-20-9) are valuable in exploring how changes in peptide sequence and structure affect biological activity and specificity. 

4. Analytical and Practical Considerations：

1）Purification：Peptides synthesized with Fmoc-Ile-Aib-OH(CAS number 2171139-20-9) are typically purified using chromatographic techniques (e.g., HPLC) to isolate and characterize the desired peptide product.

2）Characterization：Analytical methods such as mass spectrometry and NMR spectroscopy confirm the sequence, purity, and structural integrity of synthesized peptides.