Products

OCTADECANEDIOIC ACID MONO-TERT-BUTYL ESTER

CAS:843666-40-0

Quantity:

DMF Num:843666-40-0

Basic information

CAS NO. 843666-40-0
Purity  ≥98%
English name OCTADECANEDIOIC ACID MONO-TERT-BUTYL ESTER
Molecular formula C22H42O4
Molecular weight 370.57
Storage conditions 2-8°C
Character white to off-white powder

Description

Key Features

Selective Ester Protection:Monotertertiary butyl ester group enables orthogonal deprotection in complex syntheses.

Long-Chain Hydrophobicity:18-carbon backbone enhances lipid solubility and membrane interaction in pharmaceutical formulations.

Low Impurity Profile:Single impurity ≤0.5%, total impurities ≤1.0%.

 

Applications

Drug Delivery System Development:

Lipid-d nanoparticle synthesis for mRNA vaccines (e.g., polyethylene glycol conjugation via terminal carboxyl group).

Emulsifier in parenteral formulations, improving drug solubility by 40% compared to standard esters.

Polymer Chemistry:

Precursor for biodegradable polyesters (e.g., poly(ester amide)) used in surgical sutures and drug-eluting implants.

Co-monomer in polyurethane synthesis, enhancing material flexibility and thermal stability.

Biomedical Research:

Lipid b model studies: Forms stable monos at the air-water interface for membrane protein research.

bolic pathway labeling: Isotopically labeled analogs (¹³C, ²H) for fatty acid oxidation studies.

 

Manufacturing Standards

GMP-Compliant Facility:Produced in an ISO 9001:2015 & ISO 14001 certified plant with strict QC protocols.

Global Regulatory Support:Provides DMF, CE, REACH, and US FDA DMF documentation for pharmaceutical applications.

Stability Testing:Validated for 24 months under 2-8°C.

 

Analytical Data

843666-40-0 HNMR

843666-40-0 LCMS

 

Services Offered

Custom Modifications:Isotopic labeling (¹³C, ²H), functional group modification (e.g., alkyne, azide), and polymer conjugation.

Scalable Production:100 g to 50 kg batches, supporting from R&D to commercial manufacturing.

Technical Consultation:Free formulation advice by our PhD-level materials science team.

 

Company Profile

15+ Years Experience:Specialized in peptide intermediates for global pharma and biotech industries.

R&D Capability:30+ scientists in a 2,000㎡ state-of-the-art laboratory.

Global FootprintServed 500+ clients in 30+ countries, including top 10 global pharma companies.

 

Contact Us

Email:export@pu-kang.com

Phone:+86-137-0808-4407

Address:Zone 1 and 2, 1-3F, Building 3, Chengdu Cross-Strait Science and Technology Industrial Development Park [Jindi Weixin Wenjiang Intelligent Park], Wenjiang District, Chengdu, China.

Tag

CAS-843666-40-0