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Fmoc-His-Aib-OH TFA

CAS:1446013-08-6

Quantity:

DMF Num:1446013-08-6

Basic information

CAS NO. 1446013-08-6
Purity /
English name Fmoc-His-Aib-OH TFA
Molecular formula C27H27F3N4O7
Molecular weight 576.53
Storage conditions Below -20 ° C
Character powder

Description

Key Features

Fmoc Protection:Optimized for solid-phase peptide synthesis (SPPS), enabling efficient coupling in GLP-1 analog development.

Aib Residue:Introduces backbone rigidity, enhancing bolic stability in long-acting peptides.

Low Impurity Profile:Single impurity ≤0.5%, total impurities ≤1.0% (COA available upon request).

 

Applications

Semaglutide & GLP-1 Agonist Synthesis:Critical for constructing the His-Aib motif in Semaglutide's amino acid sequence, improving synthetic efficiency by 20%+ compared to standard derivatives.

Peptide Drug Discovery:Suitable for library screening in obesity, diabetes, and bolic disease research.

cGMP-Compliant Production:Scalable from 100 mg to 5 kg batches, supporting preclinical research to commercial manufacturing.

 

Regulatory Compliance

ISO 9001:2015 & ISO 14001 Certified:Manufactured in a cGMP-compliant facility with strict quality control.

Global Regulatory Support:Provides DMF, CE, and REACH registration documents for EU/US markets.

Stability Testing:Validated for 24 months under -20°C dry storage.

 

Analytical Data

1446013-08-6 HNMR

1446013-08-6 LCMS

 

Services Offered

Custom Modifications:Alternative protection groups (e.g., Boc, Cbz) or isotopic labeling upon request.

Rush Services:24-hour turnaround for urgent orders (subject to availability).

Technical Consultation:Free peptide synthesis optimization by our PhD-level chemists.

 

Company Profile

15+ Years Experience:Specialized in peptide intermediates for global pharma and biotech industries.

R&D Capability:30+ scientists in a 2,000㎡ state-of-the-art laboratory.

Global FootprintServed 500+ clients in 30+ countries, including top 10 global pharma companies.

 

Contact Us

Email:export@pu-kang.com

Phone:+86-137-0808-4407

Address:Zone 1 and 2, 1-3F, Building 3, Chengdu Cross-Strait Science and Technology Industrial Development Park [Jindi Weixin Wenjiang Intelligent Park], Wenjiang District, Chengdu, China.

Tag

CAS-1446013-08-6