Boc-L-His(Trt)-Aib-OH is an important peptide compound. This article will introduce in detail its basic information, physical and chemical properties, uses and safety.

1. Basic information

2061897-68-3

Chemical Name:Boc-L-His(Trt)-Aib-OH

Synonyms：

Boc-His(Trt)-Aib-OH;BOC-L-HIS(TRT)-AIB-OH;Semaglutide Chain Chian;(Tert-Butoxy)Carbonyl L-His(Trt)-Aib-OH;BOC-L-HIS(TRT)-AIB-OH，Semaglutide sidechain;N-BOC-N' -triphenylmethyl-L-histaminoyl-2-methylalanine;(S)-2-[2-(Boc-amino)-3-(1-trityl-4-imidazolyl)propanamido]-2-methylpropanoic Acid;(S)-2-(2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid;2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propanamido]-2-methylpropanoic acid

Product Deion

Boc-His(Trt)-Aib-OH, a highly specialized peptide synthesis reagent employed within the biomedical industry, presents a powerful capability for the creation of peptide sequences inclusive of unconventional amino acids. Its steadfast utilization helps to promote the generation of distinct and optimal peptide architectures, critical for the progression of targeted drug development, including the likes of Alzheimer's disease, cancer and many other diseases.

2、Physical and chemical properties

Boc-His(Trt)-Aib-OH has a melting point above 171°C (decomposition), a predicted boiling point of approximately 789.3±60.0°C, and a density of approximately 1.17±0.1 g/cm³. This compound is slightly soluble in chloroform and DMSO, but less soluble in water. These physical and chemical properties provide an important reference for its laboratory synthesis and purification process.

3、Use

The compound with CAS number 2061897-68-3 has a wide range of applications in biological and pharmaceutical fields. First, it serves as a starting material for the synthesis of semaglutide, a drug used to treat diabetes, which is of great significance for the industrial production of this drug. Secondly, the compound can also be used in scientific research, especially as an important intermediate or modifying agent in the synthesis and modification process of peptide drugs. In addition, due to the specificity of its structure, this compound may also play an important role in the synthesis of other biologically active substances.

4、Security

Although Boc-His(Trt)-Aib-OH has wide applications in laboratories and industries, safety still needs to be paid attention to during its use. According to the information provided in the Safety Data Sheet (MSDS), this compound may cause certain harm to human health, such as skin irritation, eye damage, etc. Therefore, appropriate personal protective equipment should be worn during use and relevant safe operating procedures should be followed. At the same time, ensure that the product is kept under appropriate storage conditions to avoid changes in its properties.

As an important peptide intermediate, the compound with CAS number 2061897-68-3 has broad application prospects in the biological and pharmaceutical fields. With the continuous development of science and technology, the synthesis methods and application fields of this compound will continue to be expanded and improved. At the same time, we should also pay attention to its safety issues to ensure that risks can be minimized during use.

If you happen to have this need, please contact us.