The article about CAS No. 1446013-08-6 mainly introduces the compound Fmoc-protected dipeptide trifluoroacetate (English name: Fmoc-His-Aib-OH TFA). Here are the details:

1. Basic information

CAS number: 1446013-08-6

Chinese name: Fmoc protected dipeptide trifluoroacetate

English name: Fmoc-His-Aib-OH TFA

Alias: FMOC-HIS-AIB-OH TFA; N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine-2-methyl-alanine 2,2,2-tri Fluoroacetate

Molecular formula: C27H27F3N4O7

Molecular weight: 576.53

2. Physical properties

Appearance: solid powder (Solid:particulate/powder)

Vapor pressure: 0.17Pa at 20℃

LogP: 0.651 at 25℃ and pH7.2

3. Application and purpose

Fmoc protected dipeptide trifluoroacetate, as a pharmaceutical intermediate, has important applications in drug synthesis and biochemical research. It is commonly used in the synthesis of peptides and proteins as a protecting group to stabilize amino acid residues and remove them through appropriate conditions in subsequent steps.

4. Safety information

Regarding the safety information of this compound, such as toxicity, irritation, flammability, etc., it is recommended to consult the relevant safety data sheet (MSDS) for detailed information. During use and storage, relevant safety operating procedures should be strictly followed to ensure the safety of personnel and the environment.

Industry background

1. Pharmaceutical intermediates industry

1446013-08-6, as a pharmaceutical intermediate, occupies an important position in drug synthesis and biochemical research. Pharmaceutical intermediates are key compounds in the synthesis process of pharmaceutical raw materials. Their quality and purity directly affect the efficacy and safety of the final drug.

2. Peptide synthesis and drug development

Peptide drugs have broad application prospects in the medical field due to their unique biological activity and low toxicity. 1446013-08-6, as an important raw material in peptide synthesis, provides strong support for the development and production of peptide drugs.

Industry application

1. Drug synthesis

During the drug synthesis process, Fmoc-protected dipeptide trifluoroacetate serves as a protective group to stabilize amino acid residues and prevent unnecessary reactions during the synthesis process. By gradually removing protective groups and linking other amino acid residues, peptides or protein drugs with specific sequences and biological activities can be synthesized.

2. Biochemical research

In biochemical research, the Fmoc-protected dipeptide trifluoroacetate is also used as a research tool. Researchers can use their unique chemical properties to explore the structure and function relationships of peptides and proteins, providing new ideas and methods for disease diagnosis and treatment.

Industry development trends

1. Technological innovation

With the continuous development of synthetic chemistry and biotechnology, the synthesis methods and technologies of peptide drugs are also constantly innovating. In the future, the synthesis process of Fmoc-protected dipeptide trifluoroacetate will be more efficient, environmentally friendly and sustainable, providing more convenience for drug development and production.

2. Growth in market demand

As the population ages and the incidence of chronic diseases increases, the demand for peptide drugs is also increasing. This will promote the continued growth of market demand for pharmaceutical intermediates such as Fmoc-protected dipeptide trifluoroacetate.

3. Impact of regulations and policies

Regulations and policies in the pharmaceutical industry have an important impact on the production and use of pharmaceutical intermediates. In the future, with the continuous improvement and tightening of domestic and foreign regulations and policies, the production and use of pharmaceutical intermediates will be more standardized and standardized, placing higher requirements on the quality and safety of products such as Fmoc-protected dipeptide trifluoroacetate.